Discover the exceptional rarity of redheads with blue eyes, a genetic combination that represents only 0.17% of the population. That is, about one person in a million.
In our world, the diversity of hair and eye colors is amazing. There are countless shades and combinations, each with its own unique intensity, brightness and undertones. The variety is virtually endless, allowing each person to be truly unique in their appearance.
In addition, the diversity of hair and eye color combinations is influenced by factors such as genetics and ethnic mix. However, there is an extremely rare combination that affects only one in a million peoplemaking it a true rarity among the human population.
He World Atlas shows that the vast majority of the world’s population, about 75-85% have dark brown or black hair. Also, between 70% and 79% of people have brown eyes. These statistics reflect the prevalence of these colors in the world’s population.
According to dr. Julie Kaplan, a leading genetics expert at the Cleveland Clinic’s Center for Personalized Genetic Health, hair color is linked to certain genetic variations. His research reveals the close relationship between genetics and hair pigmentationunraveling the mysteries behind the diversity of colors we see in humans.
The role of genes in color variation
This has been proven by scientific research the most unusual hair color is deep redespecially if a father has brown hair and a mother is blonde.
This uniqueness is mainly attributed to the MC1R gene, which plays a crucial role in determining hair, skin and eye color.. The rarest hair color is red due to the scarcity of genetic variants associated with this shade.
The MC1R gene plays a critical role in determining hair color, and only three of its variants have been identified as being related to red hair. But even those with only one variant are more likely to have red or red-blonde hair.
This discovery highlights the complexity of genetic factors that influence the diversity of hair colors seen in humans. In addition, the other six variants of the MC1R gene have the ability to generate a wide variety of hair colors ranging from shades of blonde to brown.

With regard to the ocular part, it is important to emphasize that just as the MC1R gene influences hair color, there is a gene known as OCA2 that plays a key role in determining eye color.
In fact, it is estimated that about 75% of the variation in eye color can be attributed to this gene. The OCA2 gene is responsible for the production and distribution of pigments in the iris.which affects the tonality of the eyes.
The rarest combination of hair and eye color
Now the rarest combination of hair and eye color in humans is red hair and blue eyes.
A fascinating discovery is the presence of another gene called HERC2, which interacts with the MC1R gene and the OCA2 gene. The HERC2 gene has been discovered to be able to turn off the redhead gene while expressing blue eyes and blond hair.
This genetic combination makes the presence of blue eyes and red hair even more exceptional. In fact, it is fascinating to discover that only one in a million people in the entire world have these unique colors in their eyes and hair.
According to a study conducted by the professor of evolutionary biology, Mark Elgar, from the University of Melbourne, it has been verified that red-haired people with blue eyes are extremely rare, representing only 0.17% of the population.